Substance Information Guide
Educational information about psychedelic substances. This guide is for educational purposes only and does not encourage or facilitate illegal activity.
Medical Disclaimer & Safety Notice
This information is for educational purposes only and is not medical advice.
- Always consult qualified healthcare professionals before considering any substance
- Many substances listed are controlled or illegal in most jurisdictions
- Psychedelic substances can pose serious physical and psychological risks
- Individual responses vary greatly; what is safe for one person may not be for another
- Pre-existing conditions, medications, and other factors significantly affect safety
- This information does not constitute encouragement or endorsement of illegal activities
If you are experiencing mental health challenges, please contact a licensed mental health professional or emergency services in your area.
2C-B
2C-B (2,5-dimethoxy-4-bromophenethylamine) is a psychoactive synthetic drug in the phenethylamine family. It is sometimes categorized as both a psychedelic and a stimulant, depending on dose and context. Below is a clear, educational explanation focusing on history, effects, risks, and legal status.
5-MeO-DMT
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Ayahuasca
Traditional plant medicine containing DMT and MAO inhibitors
Cacao
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Cannabis
Cannabis plant with psychoactive and therapeutic properties
DMT
N,N-Dimethyltryptamine, a naturally occurring psychedelic compound
Ibogaine
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Kambo
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Ketamine
Dissociative anesthetic with psychedelic properties
LSD
Lysergic acid diethylamide, a synthetic psychedelic compound
MDMA
3,4-Methylenedioxymethamphetamine, an empathogenic compound
Mescaline
Psychedelic alkaloid found in various cacti species
Peyote
Peyote is a small, spineless cactus native to northern Mexico and the southwestern United States. It grows extremely slowly (often 10–20 years to mature) and contains the psychoactive alkaloid Mescaline. For thousands of years, peyote has been used as a sacramental medicine by Indigenous peoples, especially within traditions such as the Native American Church, where it plays a central role in healing, prayer, and community ceremonies. This is not a “recreational drug” in its original context — it is a ceremonial plant teacher with strong ethical, ecological, and spiritual dimensions.
Psilocybin
Naturally occurring psychedelic compound found in various mushroom species
Rapé
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Sananga
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San Pedro
Mescaline cactus medicine
Tobacco
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Yopo
Yopo is a powerful psychedelic snuff made from the seeds of the Anadenanthera peregrina tree, used for centuries by indigenous peoples of South America and the Caribbean. It contains potent tryptamines — primarily bufotenin, DMT, and 5-MeO-DMT — and is traditionally blown into the nostrils during shamanic rituals for healing, divination, and spiritual connection.